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1

HIV-1 SUBTYPE C INFECTED CHILDREN WITH EXCEPTIONAL NEUTRALIZATION BREADTH EXHIBIT POLYCLONAL RESPONSES TARGETING KNOWN EPITOPES

Ditse, Zanele, Muenchhoff, Maximilian, Adland, Emily, Jooste, Pieter, Goulder, Philip, Moore, Penny L., Morris, Lynn

Journal:

Journal of Virology

Year:

2018

Language:

english

File:

PDF, 7.77 MB

english, 2018

2

Combined structural and immunological refinement of HIV-1 HLA-B8-restricted cytotoxic T lymphocyte epitopes

Philip J. R. Goulder, Scott W. Reid, David A. Price, Chris A. O'callaghan, Andrew J. McMichael, Rodney E. Phillips, E. Yvonne Jones

Journal:

European Journal of Immunology

Year:

1997

Language:

english

File:

PDF, 1.07 MB

english, 1997

3

Antagonism of cytotoxic T lymphocyte-mediated lysis by natural HIV-1 altered peptide ligands requires simultaneous presentation of agonist and antagonist peptides

Andrew K. Sewell, Gillian C. Harcourt, Philip J. R. Goulder, David A. Price, Rodney E. Phillips

Journal:

European Journal of Immunology

Year:

1997

Language:

english

File:

PDF, 706 KB

english, 1997

4

Inter-Continental Patterns of HIV-1 Control: HLA and the Quest for a T Cell Vaccine

Philippa Matthews, Andy Prendergast, Yuka Kawashima, Katya Pfafferott, John Frater, David Heckerman, Masafumi Takiguchi, Philip Goulder

Journal:

Journal of Infection

Year:

2009

Language:

english

File:

PDF, 48 KB

english, 2009

5

Mother-to-child transmission of HIV infection and CTL escape through HLA-A2-SLYNTVATL epitope sequence variation

Philip J.R Goulder, Christophe Pasquier, Eddie C Holmes, Bin Liang, Yanhua Tang, Jacques Izopet, Karine Saune, Eric S Rosenberg, Sandra K Burchett, Kenneth McIntosh, Martin Barnardo, Michael Bunce, Br

Journal:

Immunology Letters

Year:

2001

Language:

english

File:

PDF, 438 KB

english, 2001

6

HLArestrictor—a tool for patient-specific predictions of HLA restriction elements and optimal epitopes within peptides

Malene Erup Larsen, Henrik Kloverpris, Anette Stryhn, Catherine K. Koofhethile, Stuart Sims, Thumbi Ndung’u, Philip Goulder, Søren Buus, Morten Nielsen

Journal:

Year:

2011

Language:

english

File:

PDF, 923 KB

english, 2011

7

Co-evolution of human immunodeficiency virus and cytotoxic T-lymphocyte responses

Philip Goulder, David Price, Martin Nowak, Sarah Rowland-Jones, Rodney Phillips, Andrew McMichael

Journal:

Immunological Reviews

Year:

1997

Language:

english

File:

PDF, 4.80 MB

english, 1997

8

Rapid Characterization of HIV Clade C-Specific Cytotoxic T Lymphocyte Responses in Infected African Children and Adults

PHILIP J. R. GOULDER

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 2.63 MB

english, 2000

9

The great escape – AIDS viruses and immune control

Goulder, Philip J.R., Walker, Bruce D.

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 85 KB

english, 1999

10

10.1038/35030283

Walker, Bruce D., Goulder, Philip J. R.

Journal:

Year:

2000

Language:

english

File:

PDF, 97 KB

english, 2000

11

10.1038/35035103

Walker, Bruce D., Rosenberg, Eric S., Altfeld, Marcus, Poon, Samuel H., Phillips, Mary N., Wilkes, Barbara M., Eldridge, Robert L., Robbins, Gregory K., D'Aquila, Richard T., Goulder, Philip J. R.

Journal:

Year:

2000

Language:

english

File:

PDF, 288 KB

english, 2000

12

10.1038/35085576

Goulder, Philip J. R., Brander, Christian, Tang, Yanhua, Tremblay, Cecile, Colbert, Robert A., Addo, Marylyn M., Rosenberg, Eric S., Nguyen, Thi, Allen, Rachel, Trocha, Alicja, Altfeld, Marcus, He, Su

Journal:

Year:

2001

Language:

english

File:

PDF, 193 KB

english, 2001

13

'Unleashed' natural killers hinder HIV

Altfeld, Marcus, Goulder, Philip

Journal:

Nature Genetics

Year:

2007

Language:

english

File:

PDF, 272 KB

english, 2007

14

Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

Goulder, Philip J.R., Phillips, Rodney E., Colbert, Robert A., McAdam, Stephen, Ogg, Graham, Nowak, Martin A., Giangrande, Paul, Luzzi, Graz, Morgana, Barbara, Edwards, Anne

Journal:

Nature Medicine

Year:

1997

File:

PDF, 613 KB

1997

15

HIV and SIV CTL escape: implications for vaccine design

Goulder, Philip J. R., Watkins, David I.

Journal:

Nature Reviews Immunology

Year:

2004

Language:

english

File:

PDF, 258 KB

english, 2004

16

Impact of MHC class I diversity on immune control of immunodeficiency virus replication

Goulder, Philip J. R., Watkins, David I.

Journal:

Nature Reviews Immunology

Year:

2008

Language:

english

File:

PDF, 711 KB

english, 2008

17

Dimethyl sulfoxide (DMSO) exposure to human peripheral blood mononuclear cells (PBMCs) abolish T cell responses only in high concentrations and following coincubation for more than two hours

Henrik Kloverpris, Anders Fomsgaard, Amanda Handley, Jim Ackland, Mark Sullivan, Philip Goulder

Journal:

Journal of Immunological Methods

Year:

2010

Language:

english

File:

PDF, 988 KB

english, 2010

18

Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality

Nompumelelo Mkhwanazi, Christina F. Thobakgale, Mary van der Stok, Shabashini Reddy, Zenele Mncube, Fundisiwe Chonco, Bruce D. Walker, Marcus Altfeld, Philip J.R. Goulder, Thumbi Ndung'u

Journal:

Year:

2010

Language:

english

File:

PDF, 845 KB

english, 2010

19

Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses

Rika Draenert, Marcus Altfeld, Christian Brander, Nesli Basgoz, Colleen Corcoran, Alysse G. Wurcel, David R. Stone, Spyros A. Kalams, Alicja Trocha, Marylyn M. Addo, Philip J.R. Goulder, Bruce D. Walk

Journal:

Journal of Immunological Methods

Year:

2003

Language:

english

File:

PDF, 302 KB

english, 2003

20

Antigen–specific release of β-chemokines by anti-HIV-1 cytotoxic T lymphocytes

David A. Price, Andrew K. Sewell, Tao Dong, Rusung Tan, Philip J.R. Goulder, Sarah L. Rowland-Jones, Rodney E. Phillips

Journal:

Current Biology

Year:

1998

Language:

english

File:

PDF, 130 KB

english, 1998

21

The impact of differential antiviral immunity in children and adults

Prendergast, Andrew J., Klenerman, Paul, Goulder, Philip J. R.

Journal:

Nature Reviews Immunology

Year:

2012

Language:

english

File:

PDF, 499 KB

english, 2012

22

International perspectives, progress, and future challenges of paediatric HIV infection

Andrew Prendergast, Gareth Tudor-Williams, Prakash Jeena, Sandra Burchett, Philip Goulder

Journal:

Year:

2007

Language:

english

File:

PDF, 163 KB

english, 2007

23

HIV and HLA Class I: An Evolving Relationship

Goulder, Philip J.R., Walker, Bruce D.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.23 MB

english, 2012

24

Characterization of anti-HIV-1 neutralizing and binding antibodies in chronic HIV-1 subtype C infection

Archary, Derseree, Rong, Rong, Gordon, Michelle L., Boliar, Saikat, Madiga, Maphuti, Gray, Elin S., Dugast, Anne-Sophie, Hermanus, Tandile, Goulder, Philip J.R., Coovadia, Hoosen M., Werner, Lise, Mor

Journal:

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

25

HIV-1 subtype C envelope characteristics associated with divergent rates of chronic disease progression

Derseree Archary, Michelle L Gordon, Taryn N Green, Hoosen M Coovadia, Philip JR Goulder, Thumbi Ndung'u

Journal:

Year:

2010

Language:

english

File:

PDF, 1.28 MB

english, 2010

26

Factors Influencing T Cell Activation and Programmed Death 1 Expression in HIV-Infected Children

Prendergast, Andrew, O'Callaghan, Maria, Menson, Esse, Hamadache, Djamel, Walters, Sam, Klein, Nigel, Goulder, Philip

Journal:

AIDS Research and Human Retroviruses

Year:

2011

Language:

english

File:

PDF, 166 KB

english, 2011

27

HIV-1 Superinfection — A Word of Caution

Goulder, Philip J.R., Walker, Bruce D.

Journal:

Boston Medical and Surgical Journal

Year:

2002

Language:

english

File:

PDF, 57 KB

english, 2002

28

Early and non-reversible decrease of CD161++/mucosal associated invariant T cells in HIV infection

Cosgrove, Cormac, Ussher, James E., Rauch, Andri, Gärtner, Kathleen, Kurioka, Ayako, Hühn, Michael H., Adelmann, Krista, Kang, Yu-Hoi, Fergusson, Joannah R., Simmonds, Peter, Goulder, Philip, Hansen,

Journal:

Journal of Infection

Year:

2013

Language:

english

File:

PDF, 181 KB

english, 2013

29

Positive Selection of HIV-1 Cytotoxic T Lymphocyte Escape Variants during Primary Infection

David A. Price, Philip J. R. Goulder, Paul Klenerman, Andrew K. Sewell, Philippa J. Easterbrook, Maxine Troop, Charles R. M. Bangham and Rodney E. Phillips

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1007 KB

english, 1997

30

Copresentation of Natural HIV-1 Agonist and Antagonist Ligands Fails to Induce the T Cell Receptor Signaling Cascade

Marco A. Purbhoo, Andrew K. Sewell, Paul Klenerman, Philip J. R. Goulder, Katherine L. Hilyard, John I. Bell, Bent K. Jakobsen and Rodney E. Phillips

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.66 MB

english, 1998

31

Epidemiology and impact of HIV coinfection with Hepatitis B and Hepatitis C viruses in Sub-Saharan Africa

Matthews, Philippa C., Geretti, Anna Maria, Goulder, Philip J.R., Klenerman, Paul

Journal:

Journal of Clinical Virology

Year:

2014

Language:

english

File:

PDF, 2.32 MB

english, 2014

32

Paediatric PARV4 infection in South Africa: relationship to age, maternal PARV4 status, and HIV infection

Matthews, Philippa, Sharp, Colin, Malik, Amna, Adland, Emily, Jooste, Pieter, Goulder, Philip, Simmonds, Peter, Klenerman, Paul

Journal:

BMC Infectious Diseases

Year:

2014

Language:

english

File:

PDF, 74 KB

english, 2014

33

Characterizing the epidemiology and interaction between HIV-1 and HBV co-infection in South Africa

Matthews, Philippa C, Beloukas, Apostolos, Malik, Amna, Ndung’u, Thumbi, Goulder, Philip, Geretti, Anna, Klenerman, Paul

Journal:

BMC Infectious Diseases

Year:

2014

Language:

english

File:

PDF, 75 KB

english, 2014

34

Identification of Conserved Subdominant HIV Type 1 CD8 + T Cell Epitopes Restricted Within Common HLA Supertypes for Therapeutic HIV Type 1 Vaccines

Karlsson, Ingrid, Kløverpris, Henrik, Jensen, Kristoffer Jarlov, Stryhn, Anette, Buus, Søren, Karlsson, Annika, Vinner, Lasse, Goulder, Philip, Fomsgaard, Anders

Journal:

AIDS Research and Human Retroviruses

Year:

2012

Language:

english

File:

PDF, 333 KB

english, 2012

35

Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: Association with disease progression and influence of immune pressure

Mann, Jaclyn K., Chopera, Denis, Omarjee, Saleha, Kuang, Xiaomei T., Le, Anh Q., Anmole, Gursev, Danroth, Ryan, Mwimanzi, Philip, Reddy, Tarylee, Carlson, Jonathan, Radebe, Mopo, Goulder, Philip J.R.,

Journal:

Year:

2014

Language:

english

File:

PDF, 2.46 MB

english, 2014

36

The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individuals

Addo, M. M., Altfeld, M., Rosenberg, E. S., Eldridge, R. L., Philips, M. N., Habeeb, K., Khatri, A., Brander, C., Robbins, G. K., Mazzara, G. P., Goulder, P. J. R., Walker, B. D.

Journal:

Proceedings of the National Academy of Sciences

Year:

2001

Language:

english

File:

PDF, 121 KB

english, 2001

37

Transmitted Escape Mutations Lead to Accelerated HIV-1 Disease Progression and Largely Define the Relative Contribution of HLA Alleles to Control

Carlson, Jonathan M., Schaefer, Malinda, Brumme, Chanson, Pfeifer, Nico, Shapiro, Roger, Ndung'u, Thumbi, Frater, John, Mallal, Simon, John, Mina, Heckerman, David, Goulder, Philip, Brumme, Zabrina, H

Journal:

AIDS Research and Human Retroviruses

Year:

2014

Language:

english

File:

PDF, 65 KB

english, 2014

38

HIV Minor Variants Detected by Next Generation Sequencing: Impact on Immune Control of HIV in the Context of HLA-B27:05 and HLA-B57:01

Brener, Jacqui, Gall, Astrid, Batorsky, Rebecca, Kellam, Paul, Allen, Todd, Matthews, Philippa, Goulder, Philip

Journal:

AIDS Research and Human Retroviruses

Year:

2014

Language:

english

File:

PDF, 86 KB

english, 2014

39

Phenotypic and Functional Characteristics of Siglec-7, NKG2A and NKG2C Expressing NK Cells in Chronic HIV-1 Clade C Infection

Zulu, Michael Z., Naidoo, Kewreshini, Mncube, Zenele, Jaggernath, Manjeetha, Goulder, Philip, Ndung'u, Thumbi, Altfeld, Marcus, Thobakgale, Christina

Journal:

AIDS Research and Human Retroviruses

Year:

2014

Language:

english

File:

PDF, 62 KB

english, 2014

40

Innate Lymphoid Cells Are Depleted in HIV Infection

Kløverpris, Henrik N., Noorbhai, Aslam, Kuhn, Warren, Yadon, Marisa, Ramsuran, Duran, Nhamoyebonde, Sheperd, Kasprowicz, Victoria, Walker, Bruce, Ndung'u, Thumbi, Goulder, Philip, Karim, Abdool S., Mj

Journal:

AIDS Research and Human Retroviruses

Year:

2014

Language:

english

File:

PDF, 62 KB

english, 2014

41

Novel, Cross-Restricted, Conserved, and Immunodominant Cytotoxic T Lymphocyte Epitopes in Slow Progressors in HIV Type 1 Infection

GOULDER, PHILIP J.R., BUNCE, MIKE, KRAUSA, PETER, McINTYRE, KARL, CROWLEY, SIOBHAN, MORGAN, BARBARA, EDWARDS, ANNE, GIANGRANDE, PAUL, PHILLIPS, RODNEY E., McMICHAEL, ANDREW J.

Journal:

AIDS Research and Human Retroviruses

Year:

1996

Language:

english

File:

PDF, 1.04 MB

english, 1996

42

Impairment of CD1d-Restricted Natural Killer T Cells in Chronic HIV Type 1 Clade C Infection

Mureithi, Marianne W., Cohen, Kristen, Moodley, Ramona, Poole, Danielle, Mncube, Zenele, Kasmar, Anne, Moody, D. Branch, Goulder, Philip J.R., Walker, Bruce D., Altfeld, Marcus, Ndung'u, Thumbi

Journal:

AIDS Research and Human Retroviruses

Year:

2010

Language:

english

File:

PDF, 615 KB

english, 2010

43

TRIM5α Improves CD8+ T-cell Antiviral Activity and Synergize Intrinsic Restriction and Adaptive Immunity in HIV-1 Infected Cells

Jimenez, Esther, Kloverpis, Henrik, Peña, Ruth, Izquierdo-Useros, Nuria, Bonaventura, Clotet, Goulder, Philip, Towers, Greg, Prado, Julia G.

Journal:

AIDS Research and Human Retroviruses

Year:

2014

Language:

english

File:

PDF, 79 KB

english, 2014

44

CTL escape - progress in identifying therapeutic avenues to control HIV viraemia

Goulder, Philip JR

Journal:

Expert Opinion on Therapeutic Targets

Year:

2000

Language:

english

File:

PDF, 336 KB

english, 2000

45

IVA: accurate de novo assembly of RNA virus genomes

Hunt, Martin, Gall, Astrid, Ong, Swee Hoe, Brener, Jacqui, Ferns, Bridget, Goulder, Philip, Nastouli, Eleni, Keane, Jacqueline A., Kellam, Paul, Otto, Thomas D.

Journal:

Year:

2015

Language:

english

File:

PDF, 192 KB

english, 2015

46

Impact of HLA-B*35 subtype differences on HIV disease outcome in Mexico

Juarez-Molina, Claudia I., Valenzuela-Ponce, Humberto, Avila-Rios, Santiago, Garrido-Rodriguez, Daniela, Garcia-Tellez, Thalía, Soto-Nava, Maribel, Garcia-Morales, Claudia, Goulder, Philip, Reyes-Tera

Journal:

Year:

2014

Language:

english

File:

PDF, 669 KB

english, 2014

47

HLA-B*35

Mori, Masahiko, Wichukchinda, Nuanjun, Miyahara, Reiko, Rojanawiwat, Archawin, Pathipvanich, Panita, Maekawa, Tomoyuki, Miura, Toshiyuki, Goulder, Philip, Yasunami, Michio, Ariyoshi, Koya, Sawanpanyal

Journal:

Year:

2014

Language:

english

File:

PDF, 9.37 MB

english, 2014

48

A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape

Kløverpris, Henrik N, Cole, David K, Fuller, Anna, Carlson, Jonathan, Beck, Konrad, Schauenburg, Andrea J, Rizkallah, Pierre J, Buus, Søren, Sewell, Andrew K, Goulder, Philip

Journal:

Year:

2015

Language:

english

File:

PDF, 2.14 MB

english, 2015

49

Reply to Jefferys: Declining HIV virulence

Payne, Rebecca, Muenchhoff, Maximilian, Goulder, Philip J. R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 534 KB

english, 2015

50

Immunity to HIV in Early Life

Muenchhoff, Maximilian, Prendergast, Andrew J., Goulder, Philip Jeremy Renshaw

Journal:

Frontiers in Immunology

Year:

2014

Language:

english

File:

PDF, 813 KB

english, 2014

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